Generic medicine information · JAK inhibitor · Prescription-only

Baricitinib: the oral JAK inhibitor, its originator Olumiant and listed products

Baricitinib is a once-daily oral Janus kinase (JAK) inhibitor. In the United States it is approved as Olumiant for adults with rheumatoid arthritis after a TNF blocker, for hospitalised adults with COVID-19 who need oxygen, and for severe alopecia areata.[1][3]

This page explains the medicine using official sources and lists 10 products as listed by their suppliers, plus the originator Olumiant. It is not a complete global list, and regulatory status differs by product and country.[5]

Availability enquiries are handled by Medicine for World. Submission of an enquiry does not confirm regulatory eligibility, supply or delivery. Ownership and commercial disclosure

Baricent (2 / 4 mg) pack, manufacturer as listed: Incepta Pharma
Baricinix (2 / 4 mg) pack, manufacturer as listed: Beacon Pharma
Barudx (2 / 4 mg) pack, manufacturer as listed: Bigbear Pharma
Baricent · Baricinix · Barudx — Product photos as listed[5]
  • 11 brands includedOriginator plus 10 listed products
  • Originator: OlumiantEli Lilly · EU 2017, US 2018
  • Regulatory status variesConfirm with your national authority
  • Prescription-only medicineBoxed warning in the US label
Quick facts

Baricitinib at a glance

Generic name (INN)
Baricitinib[1]
Medicine class
Janus kinase (JAK) inhibitor, taken by mouth[1]
Dosage form
Film-coated tablet, once daily, with or without food[1]
Strengths (US label)
1 mg, 2 mg, 4 mg[1]
Originator
Olumiant · Eli Lilly and Company (discovered by Incyte)[1][4]
First approvals
European Union: 13 February 2017 · United States: 2018[2][1]
Products in this directory
11 brands total · 10 listed products plus Olumiant[5]
Supply status
Prescription-only medicine[1]

What is baricitinib?

Baricitinib is the international non-proprietary name of an oral Janus kinase (JAK) inhibitor. JAK enzymes pass on signals from several cytokines involved in inflammation and immune responses; baricitinib reduces this signalling.[1]

According to the current US prescribing information (DailyMed, revised June 2026), Olumiant is indicated for:[1]

  • adults with moderately to severely active rheumatoid arthritis who have had an inadequate response to one or more TNF blockers;
  • hospitalised adults with COVID-19 who need supplemental oxygen, non-invasive or invasive mechanical ventilation, or ECMO;
  • severe alopecia areata. On 25 September 2026 the FDA extended this use to patients 12 years and older; the label version cited here predates that change.[3]

In the European Union, where it was first authorised on 13 February 2017, Olumiant is authorised for rheumatoid arthritis in adults, moderate to severe atopic dermatitis in adults and children from 2 years, severe alopecia areata in adults and adolescents from 12 years, and juvenile idiopathic arthritis from 2 years. Approved uses differ between countries.[2]

Whether baricitinib is suitable, and at which dose, is decided by the treating physician. Full warnings are in the official product information:

Directory

10 products currently included in this directory

The products below are included for identification and availability-enquiry purposes. Inclusion does not mean that a product is authorised, approved, therapeutically equivalent or available in every country. Confirm regulatory status with the relevant national medicines authority.

Products are listed in alphabetical order. The list is not a ranking and makes no claim that one product is better than another.[5]

10 of 10 products

  • Baricent (2 / 4 mg) pack, manufacturer as listed: Incepta Pharma

    Baricent

    Product information listed
    Active ingredient as listed
    Baricitinib
    Manufacturer as listed
    Incepta Pharma Ltd. (manufacturing country listed: Bangladesh)
    Product strength (not a dose recommendation)
    2 / 4 mg
    Dosage form
    Tablet
    Pack information
    14 / 20 tablets, strip
    Information source
    Product listing dataset[5]
    Information last checked
    October 6, 2026
    Regulatory status
    Not independently verified for this page
  • Baricinix (2 / 4 mg) pack, manufacturer as listed: Beacon Pharma

    Baricinix

    Product information listed
    Active ingredient as listed
    Baricitinib
    Manufacturer as listed
    Beacon Pharma Ltd. (manufacturing country listed: Bangladesh)
    Product strength (not a dose recommendation)
    2 / 4 mg
    Dosage form
    Tablet
    Pack information
    30 tablets, pot (container)
    Information source
    Product listing dataset[5]
    Information last checked
    October 6, 2026
    Regulatory status
    Not independently verified for this page
  • Barigen (4 mg) pack, manufacturer as listed: General Pharma

    Barigen

    Product information listed
    Active ingredient as listed
    Baricitinib
    Manufacturer as listed
    General Pharma Ltd. (manufacturing country listed: Bangladesh)
    Product strength (not a dose recommendation)
    4 mg
    Dosage form
    Tablet
    Pack information
    30 tablets, pot (container)
    Information source
    Product listing dataset[5]
    Information last checked
    October 6, 2026
    Regulatory status
    Not independently verified for this page
  • Barinib (2 mg) pack, manufacturer as listed: Eskayef Pharma

    Barinib

    Product information listed
    Active ingredient as listed
    Baricitinib
    Manufacturer as listed
    Eskayef Pharma Ltd. (manufacturing country listed: Bangladesh)
    Product strength (not a dose recommendation)
    2 mg
    Dosage form
    Tablet
    Pack information
    30 tablets, strip
    Information source
    Product listing dataset[5]
    Information last checked
    October 6, 2026
    Regulatory status
    Not independently verified for this page
  • Barinib 2 (2 mg) pack, manufacturer as listed: General Pharma

    Barinib 2

    Product information listed
    Active ingredient as listed
    Baricitinib
    Manufacturer as listed
    General Pharma Ltd. (manufacturing country listed: Bangladesh)
    Product strength (not a dose recommendation)
    2 mg
    Dosage form
    Tablet
    Pack information
    30 tablets, pot (container)
    Information source
    Product listing dataset[5]
    Information last checked
    October 6, 2026
    Regulatory status
    Not independently verified for this page
  • Barinib-2 (2 mg) pack, manufacturer as listed: Drug International

    Barinib-2

    Product information listed
    Active ingredient as listed
    Baricitinib
    Manufacturer as listed
    Drug International Ltd. (manufacturing country listed: Bangladesh)
    Product strength (not a dose recommendation)
    2 mg
    Dosage form
    Tablet
    Pack information
    60 tablets, strip
    Information source
    Product listing dataset[5]
    Information last checked
    October 6, 2026
    Regulatory status
    Not independently verified for this page
  • Baritor (2 mg) pack, manufacturer as listed: Square Pharma

    Baritor

    Product information listed
    Active ingredient as listed
    Baricitinib
    Manufacturer as listed
    Square Pharmaceuticals Ltd. (manufacturing country listed: Bangladesh)
    Product strength (not a dose recommendation)
    2 mg
    Dosage form
    Tablet
    Pack information
    20 tablets, strip
    Information source
    Product listing dataset[5]
    Information last checked
    October 6, 2026
    Regulatory status
    Not independently verified for this page
  • Barudx (2 / 4 mg) pack, manufacturer as listed: Bigbear Pharma

    Barudx

    Product information listed
    Active ingredient as listed
    Baricitinib
    Manufacturer as listed
    Bigbear Pharma Ltd. (manufacturing country listed: Laos)
    Product strength (not a dose recommendation)
    2 / 4 mg
    Dosage form
    Tablet
    Pack information
    28 tablets, pot (container)
    Information source
    Product listing dataset[5]
    Information last checked
    October 6, 2026
    Regulatory status
    Not independently verified for this page
  • LuciBaric (2 mg) pack, manufacturer as listed: Lucius Pharma

    LuciBaric

    Product information listed
    Active ingredient as listed
    Baricitinib
    Manufacturer as listed
    Lucius Pharma Ltd. (manufacturing country listed: Laos)
    Product strength (not a dose recommendation)
    2 mg
    Dosage form
    Tablet
    Pack information
    30 tablets, pot (container)
    Information source
    Product listing dataset[5]
    Information last checked
    October 6, 2026
    Regulatory status
    Not independently verified for this page
  • Palutini (4 mg) pack, manufacturer as listed: TLPH Pharma

    Palutini

    Product information listed
    Active ingredient as listed
    Baricitinib
    Manufacturer as listed
    TLPH Pharma Ltd. (manufacturing country listed: Laos)
    Product strength (not a dose recommendation)
    4 mg
    Dosage form
    Tablet
    Pack information
    60 tablets, pot (container)
    Information source
    Product listing dataset[5]
    Information last checked
    October 6, 2026
    Regulatory status
    Not independently verified for this page

Product listing data last checked October 6, 2026.

Originator

Originator medicine: Olumiant (Eli Lilly and Company)

Olumiant is the originator baricitinib medicine. Baricitinib was discovered by Incyte and licensed to Eli Lilly and Company in 2009. Olumiant was first authorised in the European Union on 13 February 2017 and in the United States in 2018. Olumiant itself is not part of the Medicine for World listing; its card links to the official US prescribing information. Other products represented as containing baricitinib are made by other manufacturers and sold under their own brand names.[1][2][4]

The originator is shown here separately from the other listed products.

Brand name
Olumiant[1]
Active substance
Baricitinib[1]
Company
Eli Lilly and Company (US labeler); EU holder: Eli Lilly Nederland B.V.[1][2]
Strengths in the US label
Tablets: 1 mg, 2 mg and 4 mg[1]
First approvals
European Union 13 February 2017 · United States 2018[2][1]
US approved uses
Rheumatoid arthritis, hospitalised COVID-19, severe alopecia areata[1][3]
Comparison

Baricitinib generic vs originator medicine

This comparison covers identity and listing information only. It does not establish regulatory approval, pharmaceutical equivalence, bioequivalence, quality, safety or clinical effectiveness.

AttributeOther listed baricitinib productsOriginator (Olumiant)
Active substanceBaricitinib, as listed. Formulation details are not stated in the product listings.[5]Baricitinib[1]
Brand nameEach manufacturer's own brand name (10 products listed)[5]Olumiant[1]
Company9 manufacturers, with manufacturing countries listed as Bangladesh or Laos[5]Eli Lilly and Company[1]
Dosage formTablet, as listed[5]Film-coated tablet[1]
Strengths2 mg and/or 4 mg, as listed[5]1 / 2 / 4 mg[1]
Regulatory approvalVaries by product and country. Not independently verified for this page; check with your national medicines authority.EU 13 February 2017 · US 2018[2][1]
ClassificationProduct represented by its manufacturer or supplier as containing baricitinib. Regulatory classification must be confirmed in the relevant jurisdiction.[5]Originator product[1]
Safety

Side effects and important warnings

The information below summarises the US prescribing information. It is not complete; read the full label and talk to your doctor.[1]

Boxed warning: serious infections, mortality, cancer, heart events and blood clots. Baricitinib increases the risk of serious bacterial, fungal, viral and opportunistic infections, including tuberculosis, that can lead to hospitalisation or death; people are tested for latent tuberculosis before and during treatment, except for COVID-19. With another JAK inhibitor compared with TNF blockers in rheumatoid arthritis, higher rates of death from any cause, lymphoma and lung cancer, major heart events and blood clots were seen. Cancers and blood clots have also occurred in people treated with baricitinib.[1]

Common side effects in the US label (compared with placebo)

Side effectReported in
Upper respiratory tract infections (RA, 2 mg)16.3% (placebo 11.7%)
Nausea (RA, 2 mg)2.7% (placebo 1.6%)
Herpes zoster / shingles (RA, 2 mg)1.0% (placebo 0.4%)
Herpes simplex (RA, 2 mg)0.8% (placebo 0.7%)
Headache (alopecia areata, 4 mg)6.6% (placebo 5.4%)
Acne (alopecia areata, 4 mg)5.9% (placebo 2.2%)
Raised blood lipids (alopecia areata, 4 mg)5.9% (placebo 3.0%)

Other warnings in the label

  • Serious infections, including tuberculosis and shingles
  • Higher risk of death (seen with another JAK inhibitor)
  • Cancers, including lymphoma and skin cancer
  • Major adverse cardiovascular events (heart attack, stroke, cardiovascular death)
  • Blood clots in the legs, lungs and arteries
  • Serious allergic reactions
  • Tears in the stomach or intestine (gastrointestinal perforation)
  • Low blood sugar in people with diabetes
  • Changes in blood counts, liver enzymes and blood lipids – regular blood tests are needed
  • Live vaccines should be avoided

Interactions, kidneys, pregnancy

  • With strong OAT3 inhibitors such as probenecid the dose is reduced (4 mg to 2 mg, or 2 mg to 1 mg).
  • Not recommended together with other JAK inhibitors, biologic DMARDs or potent immunosuppressants such as azathioprine and cyclosporine.
  • Kidney impairment: in rheumatoid arthritis 1 mg once daily if eGFR is 30 to under 60; not recommended below 30. Severe liver impairment: not recommended in rheumatoid arthritis or alopecia areata.
  • Based on animal studies, baricitinib may harm an unborn baby.
  • Do not breastfeed during treatment and for 4 days after the last dose.
Dosing

How baricitinib is taken (US label)

Baricitinib is taken by mouth once a day, with or without food. Blood counts are checked first: in rheumatoid arthritis and alopecia areata it should not be started if haemoglobin is below 8 g/dL, lymphocytes below 500 cells/mm³ or neutrophils below 1000 cells/mm³. Your doctor decides the dose.[1]

UseDaily doseNotes
Rheumatoid arthritis (adults)2 mg once dailyAlone or with methotrexate or other non-biologic DMARDs
COVID-19 (hospitalised adults)4 mg once dailyFor up to 14 days or until hospital discharge, whichever comes first
Severe alopecia areata2 mg once dailyIncreased to 4 mg if the response is not adequate; 4 mg can be considered for nearly complete or complete scalp hair loss; reduced to 2 mg once the response is adequate
Rheumatoid arthritis with eGFR 30 to under 601 mg once dailyNot recommended if eGFR is below 30

The doses in the table are US label information, not a personal recommendation.[1]

What the main studies showed

Rheumatoid arthritis: in study RA-4 (527 adults after one or more TNF inhibitors), 49% on baricitinib 2 mg reached an ACR20 response at week 12, compared with 27% on placebo. In study RA-3 (684 adults after conventional DMARDs) the figures were 66% and 39%.[1]

COVID-19: in the COVID II trial (1,525 hospitalised adults), 8.1% died by day 28 with baricitinib 4 mg compared with 13.3% with placebo; the primary endpoint (death or progression to ventilation) was not statistically significant (27.8% vs 30.5%).[1]

Alopecia areata: at week 36, at least 80% scalp hair coverage (SALT ≤20) was reached by 35% and 32% of adults on 4 mg, 22% and 17% on 2 mg, and 5% and 3% on placebo in trials AA-1 and AA-2.[1] In adolescents (BRAVE-AA-PEDS) the figures were 42% (4 mg), 27% (2 mg) and 5% (placebo).[3]

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FAQ

Frequently asked questions about baricitinib

What is baricitinib?

Baricitinib is a prescription-only, once-daily oral JAK inhibitor. The originator brand is Olumiant by Eli Lilly and Company. It reduces signalling by JAK enzymes, which are involved in inflammation and immune responses.

What is baricitinib used for?

In the US: adults with rheumatoid arthritis after a TNF blocker, hospitalised adults with COVID-19 who need oxygen, and severe alopecia areata (since September 2026 also from 12 years). In the EU: rheumatoid arthritis, atopic dermatitis, severe alopecia areata and juvenile idiopathic arthritis. Approved uses differ by country.

Is baricitinib the same as tofacitinib or upadacitinib?

No. They are all oral JAK inhibitors, but they are different molecules with different approved uses and doses. The class warnings on mortality, cancer, heart events and blood clots in the US label come partly from a large study of another JAK inhibitor.

What are the most common side effects?

Upper respiratory tract infections, nausea, herpes zoster and herpes simplex in rheumatoid arthritis; headache, acne and raised blood lipids were also reported in alopecia areata. The label contains a boxed warning about serious infections, mortality, cancer, heart events and blood clots.

Can baricitinib be taken with food?

Yes. According to the US label it is taken once a day, with or without food.

What does this directory include?

10 products represented by their manufacturers or suppliers as containing baricitinib – Baricent, Baricinix, Barigen, Barinib, Barinib 2, Barinib-2, Baritor, Barudx, LuciBaric and Palutini – plus the originator Olumiant. It is not a complete global list, and inclusion does not mean that a product is authorised in any specific country.

Are the listed products equivalent to Olumiant?

This page does not establish that. Equivalence, quality and regulatory status depend on each product and each country and must be confirmed with the national medicines authority and your doctor.

How can I check availability?

Use the non-binding enquiry form on this page. Medicine for World reviews destination-country rules and may ask for a prescription before offering any option. Clicking a brand opens its product page on the Medicine for World website.

Transparency

Editorial and medical review

Current editorial and medical-review status is shown below. No independent medical review is claimed until it has been completed.

Written by
MedFactHub Editorial Team
Medically reviewed by
Independent medical review pending
Medical review date
Not yet independently reviewed
Product data last checked
October 6, 2026 (listing details as supplied; regulatory status not verified)
Independent review status
Pending; recheck immediately when official sources change and before adding any new medical claim
Sources

Sources

Medical and regulatory facts come from official product information. Product listing details come from a supplied dataset. Numbers in square brackets on this page refer to the sources below.

  1. [1]
    OLUMIANT (baricitinib) US prescribing information (DailyMed, U.S. National Library of Medicine), revised 6/2026Indications, strengths, dosing, boxed warning, warnings, side effects, interactions, clinical studies · Accessed: October 6, 2026
    Official source
  2. [2]
    European Medicines Agency – Olumiant: EPAREU first authorisation (13 February 2017), marketing authorisation holder and EU indications · Accessed: October 6, 2026
    Official source
  3. [3]Official source
  4. [4]Official source
  5. [5]
    Product listing dataset supplied by Medicine for WorldBrand name, manufacturer, strength, dosage form, pack information and product images. These listing details do not by themselves establish regulatory approval or therapeutic equivalence. · Accessed: October 6, 2026
    Supplied data – not independently verified